Iron supplementation, maternal packed cell volume, and fetal growth.

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Iron supplementation, maternal packed cell volume, and fetal growth.

Previous studies have found that there is a correlation between mothers' haemoglobin concentration or packed cell volume and infants' birth weight, and that iron supplementation increases mothers' haemoglobin concentration. The purpose of this study, using the data of a large randomised trial on iron prophylaxis during pregnancy, was to find out whether iron supplementation causes fetal growth ...

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Role of iron supplementation in promoting maternal and fetal outcome

BACKGROUND The data comparing daily versus intermittent iron supplementation during pregnancy remain controversial. This study was undertaken to compare the efficacy of daily versus two different intermittent iron supplementation regimes on hematologic markers and birth outcomes in nonanemic pregnant women. METHODS Two hundred and ten women with singleton pregnancies, no known disease, and he...

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Effect of oral iron supplementation during pregnancy on maternal and fetal iron status.

The known increased need for iron during pregnancy appears to be met only in part by increased iron absorption and amenorrhea. Considerable demands are made on maternal iron stores and, since many women lack sufficient storage iron, pregnancy may be expected to cause iron deficiency. This may lead to anemia in pregnancy and post partum and could also have a bearing on the iron status of the fet...

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Maternal iron status: relation to fetal growth, length of gestation, and iron endowment of the neonate.

Anemia prevalence is highest in preschool children, women of reproductive age, and women who are pregnant. While the etiology of anemia is multifactorial, iron deficiency is the most commonly recognized nutritional cause. Observational studies imply that supplementation with iron or iron-folic acid should be started early in pregnancy, if not before, in order to prevent low-birth-weight and pre...

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Fetal iron levels are regulated by maternal and fetal Hfe genotype and dietary iron.

BACKGROUND Iron metabolism during pregnancy maintains fetal iron levels at the expense of the mother. The mechanism behind this regulation is still not clear despite recent advances. Here we examine the role of maternal and fetal Hfe, its downstream signaling molecule, hepcidin and dietary iron in the regulation of placental iron transfer. DESIGN AND METHODS Hfe wild-type, knockout and hetero...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1991

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.66.4_spec_no.422